Alzheimer's disease is a progressive, degenerative disorder that attacks the brain's nerve cells, or neurons, resulting in loss of memory, thinking and language skills, and behavioral changes.
These neurons, which produce the brain chemical, or neurotransmitter, acetylcholine, break connections with other nerve cells and ultimately die. Alzheimer's disease is the most common cause of dementia, or loss of intellectual function, among people aged 65 and older.
Causes of Alzheimer's Disease
People who get Alzheimer's disease are usually older, but the disease isn’t a normal part of aging. Scientists aren’t sure why some people get it and others don’t. But they do know that the symptoms it causes seem to come from two main types of nerve damage:
•Nerve cells get tangles, called neurofibrillary tangles.
•Protein deposits called beta-amyloid plaques build up in the brain.
Alzheimer's is a disease that robs people of their memory. At first, people have a hard time remembering recent events, though they might easily recall things that happened years ago.
As time goes on, other symptoms can appear, including:
•Trouble focusing
•A hard time doing ordinary activities
•Feeling confused or frustrated, especially at night
•Dramatic mood swings ,outbursts of anger, anxiety, and depression
•Feeling disoriented and getting lost easily
•Physical problems, such as an odd walk or poor coordination
•Trouble communicating
The Adipose-derived stem cells (ASCs),or mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency and their ability to differentiate into multiple tissue types and have immune modulatory properties similar to those of MSCs from other origins. Using adipose-derived adult stem cells from humans, we may be able to help patients regrow healthy brain tissue to address the complications associated with Alzheimer’s disease, because of their biological properties.
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